Bodybuilders and other athletes who wish to increase muscle growth utilize Dindolyl Methane (or DIM). However there have been some recent links to health hazards that DIM could cause. For instance, DIM can cause serious liver damage when consumed in excess. Kidney damage can also be an issue, and could lead to kidney failure. The potential long-term health risks associated with DIM make many bodybuilders and athletes think about the question: should I use supplements with DIM?

Most people use a diindolylmethane supplement to improve the production of testosterone. Testosterone is known to act as an androgen, which means that it causes hormonal changes in tissues. DIM has been proven in studies to mimic the effects of testosterone, as well as other hormones. Certain manufacturers have added diindolylmethane (DIM) to their products to increase their popularity in male circles because men produce more testosterone than women do. Men will react to products that mimic natural testosterone.

Many companies advertise DIM as a tumor suppressor. While diindolylmethane has been proven effective in reducing the growth of tumors in laboratory animals it was administered orally to the animals. To get the same effect in humans, diindolylmethane has to be consumed in large doses for a long period of time. The animals that were examined did not show any signs of cancer for many years. However, they all developed liver diseases due to consuming too much diindolylmethane. A doctor can give you a better understanding of the way DIM works within the body.

According to the US National Institute of Environmental Health Safety and Security, the only way to prove that DIM is effective in treating breast cancer is to perform an experiment wherein cells from healthy breast cancer cells are exposed to high doses of diindolylmethane over a prolonged period of time. Like all chemicals there are pros and cons associated with using it. The ability to mimic hormones is one of the benefits. This allows you to make insulin which can inhibit the growth of cancer cells. The cons include the fact diindolylmethane is also able to produce the potentially harmful chemical DMSO. Read more about diindolylmethane or dim here.

One of the most common claims made about diindolylmethane’s use in an treatment for various ailments is that it is an anti-cancer, natural, antibacterial and anti-fungal agent. These claims were rejected by the National Institute of Health after an exhaustive review of the supporting research. According to the Institute of Chemical Technology there were no studies which supported this assertion. The Institute of Chemical Safety, in their in-depth analysis of the safety profile of the firestone concluded that the evidence offered by pharmaceutical companies on the benefits of diindolylmethane to humans were not completely reliable.

Van der Goes, et. al. published their findings in a May 2021 issue of the Journal of Toxicology and Environmental Health. Van der Goes, et al. identified the potential risks of diindolylmethane use, including allergic reactions to the skin, asthma attacks as well as dizziness, headaches and respiratory issues. The daily dose recommended for this chemical, which is about one tenth of one teaspoon, was 0.2 milligrams. It is unclear what the concentration is when compounded with other substances. Since this substance hasn’t been thoroughly examined, it isn’t considered safe at any level.

The view abstract shows that the use of diindolylmethane for cancer treatment is based on the idea that intracellular inhibition of pyruvate metabolism via flavenoids is a possibility to block and prevents accumulation of Oxalates and pyruvate-derived metabolites in renal tubule cells. However, metabiplicate toxicology studies didn’t provide convincing evidence that consumption of this chemical causes an overdose. In June 1996, the Food and Drug Administration approved this drug as a prescription drug. According to the FDA, the manufacturer of firestone tincture is currently in the process of completing two major clinical trials – one in Europe and the other in the United States.

The abstract of the view also states that the use of diindolylmethane (DIEM) in the context of treating cancer is based on the principal of blocking intracellular inhibition of pyruvate metabolite through flavenoids, thereby preventing accumulation of oxalates in renal tubule cells and adenine granulocyte cultures. The drug metabiplicate toxicology studies have not shown that this chemical could cause overdose. The Food and Drug Administration approved the substance as a prescription drug in June 1996. According to the FDA the manufacturer of firestone Tincture is in the process of completing two major trials in Europe and the United States. According to FDA, the FDA states that the manufacturer of firestone Tincture is currently conducting two major trials in Europe as well as one in the United States.